Use of Organ-on-a-Chip technology to bridge the «valley of death» in medical devices
In this lecture, we will discuss the process of tissue regeneration, which has been studied in different lines of research with the aim of optimizing it. We will cover various aspects, such as pathophysiology, risk factors, anti-inflammatory drugs, and chemicals that may interact with healing. Among these resources, there are two methods that have demonstrated efficacy in aiding wound healing: low-intensity LED therapy and the use of natural latex derived from the Hevea brasiliensis rubber tree. We will present the use of organ platforms, which are tissue models on a chip within a microfluidic platform, and simulate the circulation and physiological behavior of the system, utilizing the latest "organ-on-chip" technology (created in his lab). We will discuss how this technology can contribute to our understanding of development, as well as serve as a valuable tool for disease modeling and drug development. Finally, we will show that the use of microfluidic systems by Biomedical Engineering and Biotechnology can serve as an alternative to high-throughput models. Speaker(s): Prof. Suélia Fleury Rosa, Virtual: https://events.vtools.ieee.org/m/449650